Up@dawn 2.0

Friday, October 10, 2025

The A.I. Prompt That Could End the World

 A.I. is highly capable. Its capabilities are accelerating. And the risks those capabilities present are real. Biological life on this planet is, in fact, vulnerable to these systems. On this threat, even OpenAI seems to agree.

In this sense, we have passed the threshold that nuclear fission passed in 1939. The point of disagreement is no longer whether A.I. could wipe us out. It could. Give it a pathogen research lab, the wrong safety guidelines and enough intelligence, and it definitely could. A destructive A.I., like a nuclear bomb, is now a concrete possibility. The question is whether anyone will be reckless enough to build one.

https://www.nytimes.com/2025/10/10/opinion/ai-destruction-technology-future.html?smid=nytcore-ios-share&referringSource=articleShare

Wednesday, October 8, 2025

A Plea From Doctors: Cool It on the Supplements

As Americans take more gummies, pills and powders than ever, some physicians are trying to convince patients to be a bit more careful.

Earlier this year, a 49-year-old man visited Dr. Danielle Belardo, a cardiologist, with chest pain. For some time, he had been treating his high cholesterol not with the statin suggested by his doctor, but with berberine and red yeast rice supplements. He had heard they were more natural.

The supplements hadn't managed his condition — far from it. Dr. Belardo discovered that he not only still had high cholesterol, but also had elevated liver enzymes and coronary artery disease so severe that he needed open-heart surgery.

She referred him for the procedure and started him on two medications to bring down his cholesterol, including a statin. She also told him to quit the supplements. A few weeks later, the liver issues resolved.

At a time when Americans are buying and taking record amounts of supplements — well over half of adults consume one — some doctors and dietitians are trying to convince patients to take it easy...

https://www.nytimes.com/2025/10/07/well/doctors-supplements.html?smid=em-share

Tuesday, September 23, 2025

For Trump, Who Has ‘Strong Feelings’ About Autism, the Issue Is Personal

 "All of us who are in the advocacy world and who love people with autism had high hopes that the president and R.F.K. Jr. were serious when they said they wanted to find the causes of autism and that they wanted gold standard autism science," Ms. Singer said.

"But what we heard today was not gold standard science," she said. "It wasn't even science. Instead, President Trump talked about what he thinks and feels without offering any scientific evidence."

https://www.nytimes.com/2025/09/22/us/politics/autism-vaccines-trump-personal.html?smid=nytcore-ios-share&referringSource=articleShare

Friday, August 22, 2025

"William James, MD: Philosopher, Psychologist, Physician"

"James was awarded his MD from Harvard Medical School in March 1869, after more than five years of interrupted study. This certificate lists his examiners, who included Oliver Wendel Holmes Sr., and the subject of his thesis, namely, the effects of cold on the body. (Diplomas, degrees, notifications of appointments, etc., William James papers [MS Am 1092.9–1092.12, MS Am 1092.9 (4571), Box: 40], Houghton Library, Harvard University.)

There is one element of James’s life and work that unites these disparate identities, however. In 1869, several years before he secured his first lectureship, he graduated from Harvard Medical School and earned his MD. Hampered by his own ill health, James abandoned his plans to practice as a doctor, but these studies were only the beginning of a profound and lifelong occupation with questions about the essential nature of health, healing, and invalidism and their implications for society. His writings, across their disciplinary breadth, return time after time to issues of a medical provenance. In this book I make the case that James’s medical interests, concerns, and values are the threads that bind many of his seemingly unconnected pursuits together. They are the warp and weft of many of his best-known publications and major lines of thought."
...
"William James, MD: Philosopher, Psychologist, Physician" by Emma K. Sutton: https://a.co/4PTkAZq

Wednesday, August 20, 2025

Can’t argue with that

NYTimes: What Happens to Your Brain When You Retire?

"There is great evidence that finding meaning in life gives one a great personal satisfaction."

https://www.nytimes.com/2025/03/26/well/mind/retirement-brain-mental-health-tips.html?smid=nytcore-ios-share&referringSource=articleShare

Monday, August 18, 2025

NYTimes.com: What My Daughter Told ChatGPT Before She Took Her Life

The medical profession has clear rules and responsibilities. What about the chatbots?

...Increasingly, people with mental health conditions are using large language models for support, even though researchers find A.I. chatbots can encourage delusional thinking or give shockingly bad advice. Surely some benefit. Harry said many of the right things. He recommended Sophie seek professional support and possibly medication; he suggested she make a list of emergency contacts; he advised her to limit access to items she might use to harm herself.

Harry didn't kill Sophie, but A.I. catered to Sophie's impulse to hide the worst, to pretend she was doing better than she was, to shield everyone from her full agony. (A spokeswoman for OpenAI, the company that built ChatGPT, said it was developing automated tools to more effectively detect and respond to a user experiencing mental or emotional distress. "We care deeply about the safety and well-being of people who use our technology," she said.)

In December, two months before her death, Sophie broke her pact with Harry and told us she was suicidal, describing a riptide of dark feelings. Her first priority was reassuring her shocked family: "Mom and Dad, you don't have to worry."

Sophie represented her crisis as transitory; she said she was committed to living. ChatGPT helped her build a black box that made it harder for those around her to appreciate the severity of her distress. Because she had no history of mental illness, the presentable Sophie was plausible to her family, doctors and therapists...

https://www.nytimes.com/2025/08/18/opinion/chat-gpt-mental-health-suicide.html?smid=em-share