Tuesday, March 12, 2024

“deliberately exposed to radiation”

'Oppenheimer,' My Uncle and the Secrets America Still Doesn't Like to Tell

…"Oppenheimer" is a movie about a singular genius, an extraordinary collaboration and a turning point in history. But it's also a lesson in applied physics: the way a lone catalyst may trigger a chain reaction whose impact cannot be predicted or controlled. J. Robert Oppenheimer's greatest triumph set into motion forces that brought about his downfall. An innovation designed to make the world safer in the long term made it manifestly more dangerous. And in subsequent atomic tests through the postwar years, many Americans were deliberately exposed to radiation, to see what the blast and its aftermath would do to them...

https://www.nytimes.com/2024/03/11/opinion/oppenheimer-secret-lives.html?smid=nytcore-ios-share&referringSource=articleShare

Pandemic lessons not learned

It has been four years since the WHO declared COVID-19 a pandemic.

In 2022 Ed Yong wrote that the U.S. "made none of the broad changes that would protect its population against future pathogens, such as better ventilation or universal paid sick leave." He predicted that America will "continue to struggle against infectious diseases in part because some of its most deeply held values are antithetical to the task of besting a virus."

https://www.threads.net/@theatlantic/post/C4YzdRnRMYY/?xmt=AQGzVL8uXjPeUw92cc_xOhRNVYs1mCOg0E7vTYMC4LycRg

Monday, March 11, 2024

‘Fantastic Voyage’-ish A.I.

A.I. Is Learning What It Means to Be Alive

Given troves of data about genes and cells, A.I. models have made some surprising discoveries. What could they teach us someday?

...“I think these models are going to help us get some really fundamental understanding of the cell, which is going to provide some insight into what life really is,” Dr. Quake said.


Having a map of what’s possible and impossible to sustain life might also mean that scientists could actually create new cells that don’t yet exist in nature. The foundation model might be able to concoct chemical recipes that transform ordinary cells into new, extraordinary ones. Those new cells might devour plaque in blood vessels or explore a diseased organ to report back on its condition.


“It’s very ‘Fantastic Voyage’-ish,” Dr. Quake admitted. “But who knows what the future is going to hold?”

..."Professors should be very, very nervous."


https://www.nytimes.com/2024/03/10/science/ai-learning-biology.html?smid=em-share

Monday, January 15, 2024

Portals

But don't underrate the value of being healthy. Things did not end well for Virginia.

"Virginia Woolf on being ill as a portal to self-understanding and a way of breaking through our ordinary waking-state perception" https://www.themarginalian.org/2019/05/06/virginia-woolf-on-being-ill/

https://www.threads.net/@mariapopova/post/C2GY6ohxDni/

Thursday, January 11, 2024

Simone de Beauvoir on the Art of Growing Older – The Marginalian

Today, and for the next few weeks, my wife is chronologically older than me. She might need to hear what Maria  Popova and Simone de Beauvoir say about time's arrow… (And happy birthday to WJ, 182 today.)


to grow old at all is a tremendous privilege — one withheld from the vast majority of humans populating the history of our young species (to say nothing of the infinite potential humans who never chanced into existing).

"…There is only one solution if old age is not to be an absurd parody of our former life, and that is to go on pursuing ends that give our existence a meaning — devotion to individuals, to groups or to causes, social, political, intellectual or creative work… In old age we should wish still to have passions strong enough to prevent us turning in on ourselves. One's life has value so long as one attributes value to the life of others, by means of love, friendship, indignation, compassion." Simone de Beauvoir 

Complement with Bertrand Russell on how to grow old and Thoreau on the greatest gift of the winter years, then revisit Simone de Beauvoir on the ultimate frontier of hope and the artist's task to liberate the present from the past.  https://www.themarginalian.org/2022/07/31/simone-de-beauvoir-coming-of-age/

https://www.themarginalian.org/2022/07/31/simone-de-beauvoir-coming-of-age/

Monday, January 8, 2024

Stephen Hawking happy

When asked about living with [ALS, Lou Gehrig's ] disease, he told an interviewer that he was "happier now" than before he became ill. "Before, I was very bored with life. I drank a fair bit, I guess; I didn't do any work . . .When one's expectations are reduced to zero, one really appreciates everything that one does have."

https://open.substack.com/pub/thewritersalmanac/p/the-writers-almanac-from-monday-january-645?r=35ogp&utm_medium=ios&utm_campaign=post

Friday, December 22, 2023

Thank goodness

I'm reading Daniel Dennett's memoir "I've Been Thinking", which begins with the near-death experience that generated my favorite written testimonial of natural gratitude.

"ON OCTOBER 24, 2006, I WAS RUSHED BY AMBULANCE from my office at Tufts University to the emergency room at Lahey Clinic, where doctors discovered the problem: the inner and outer layers of my aorta had come apart—an aortic dissection—and I could die at any moment if the blood from my heart burst out into my chest cavity. The day before I had been in Mackerel Cove on Swan’s Island in Maine on my sailboat, Xanthippe. This was the last cruise of the season, joined by my Swedish friend Bo Dahlbom and his son Fredrik, and as I slowly pulled on the heavy anchor line I felt a slight pain in my chest, reminding me of the pain I had felt seven years earlier when I’d had a “silent heart attack” that had led to a triple-bypass operation. We sailed back to Blue Hill in a stiff headwind, moored the boat, took off the heavy sails, put the inflatable dinghy on the roof of my car, and went back to the farm, before I made a quick trip to the local hospital, where I was told I had not had a heart attack but should see my cardiologist as soon as I could. The next day we drove to Tufts, where I asked the department secretary if she had any Tylenol, and she wisely called the ambulance instead.

One of the little-known side effects of open-heart surgery is ministrokes caused by debris from the operation clogging up the capillaries in the brain, and my cardiologist explicitly warned the surgical team that since my mind was my life, they should strive to avoid turning me into a “pumphead”—the ugly term heart surgeons use in private for those whose brains are damaged by the heart-lung machine. After the operation, before they removed me from the machine, they reversed the flow of blood to my brain, sending it into the veins and out of the arteries, hoping to flush out any debris that was about to disable my res cogitans, my thinking thing (my brain, not, as Descartes would have it, a distinct and immaterial substance). So I’ve been brainwashed, quite literally. Did it work? As soon as I could sit up in my hospital bed after the operation I got out my trusty laptop and wrote a short piece to see if I still had my marbles. It was put on Edge.org, where it attracted a lot of attention. What do you think?

Thank Goodness! (November 2, 2006)

There are no atheists in foxholes, according to an old but dubious saying, and there is at least a little anecdotal evidence in favor of it in the notorious cases of famous atheists who have emerged from near-death experiences to announce to the world that they have changed their minds. The British philosopher Sir A. J. Ayer, who died in 1989, is a fairly recent example. Here is another anecdote to ponder..."

Continues: https://a.co/982hZQy

Thursday, December 21, 2023

“My Year of Being Very Online About Dogs”

My friend Daryl's friend and former colleague at W.Carolina, on dogs and the culture wars. What a strange world, dogs' AND ours…

Dogs are where we project our "fantasies about what we want — either who we want to be or what we want the world to look like," said Katharine Mershon, a professor of religion and philosophy at Western Carolina University who studies the role of dogs in American society.

Dr. Mershon told me how dogs had become a focal point for tensions in her rural Appalachian town: Her local NextDoor was filled with arguments about whether leaving hunting dogs to roam about freely, slightly underfed and living mostly outside, constituted abuse. This was an argument, ostensibly about dogs, that was actually about gentrification and the place of newcomers to impose their values on local life.

At points in my conversations with Dr. Gabrielsen and Dr. Mershon, we discussed the poet, philosopher and animal trainer Vicki Hearne. "Dogs are domesticated to, and into, us," Ms. Hearne wrote in her 1986 book "Adam's Task." "And we are domesticated to, and into, them."

https://www.nytimes.com/2023/12/20/opinion/dogs-culture-wars.html?smid=nytcore-ios-share&referringSource=articleShare
My Year of Being Very Online About Dogs