Up@dawn 2.0

Tuesday, July 15, 2025

The 1st flu vaccine

Today is the birthday of microbiologist Thomas Francis Jr., born in Gas City, Indiana (1900). T.F., as he was known to his friends, grew up in western Pennsylvania and studied medicine at Yale. He graduated in 1925. His early research projects involved bacterial pneumonia, but he was particularly interested in the study of viruses. He was the first American to isolate the human influenza virus.

He joined the University of Michigan in its newly formed School of Public Health in 1941. It was here that he developed the first flu vaccine, which used the dead influenza virus to provoke an immune response in the human body. Francis had discovered in 1940 that there was more than one kind of flu virus. That's why epidemiologists release a different flu vaccine every year, based on their predictions of which strains will be dominant. It's estimated that Francis's flu vaccine has directly saved more than a million lives.

While he was teaching at the University of Michigan, Francis established a virology lab to study viruses. One of his first students in the lab was Jonas Salk. Francis taught his student how to develop vaccines, and Salk eventually went on to develop a vaccine against polio. Francis designed the massive nationwide field trial that proved the effectiveness and safety of Salk's vaccine.

Francis also founded the University of Michigan's Department of Epidemiology, to study how diseases are spread through populations and develop ways of controlling outbreaks. Francis said: "Epidemiology must constantly seek imaginative and ingenious teachers and scholars to create a new genre of medical ecologists who, with both the fine sensitivity of the scientific artist and the broad perception of the community sculptor, can interpret the interplay of forces which result in disease."

https://www.garrisonkeillor.com/radio/the-writers-almanac-for-tuesday-july-15-2025/

Thursday, July 10, 2025

Scopes at 100: America Is Still Animated by the Scopes ‘Monkey Trial’ | Cover Story | nashvillescene.com

...The challenge with teaching evolution in 2025 is the same each semester, says Elizabeth Barnes, who is now approaching her fifth year on the biology faculty at Middle Tennessee State University.

"I would say one of the biggest things that we face when we go to teach evolution is this perception that in order to accept evolution, to actually believe that evolution is a real thing, that you have to be an atheist or reject religious belief," Barnes says.

A national survey of biology students conducted by Barnes and other researchers in 2022 showed that 50 percent of the respondents believed acceptance of evolution was a rejection of God.

"That's just a misunderstanding of the nature of science," Barnes says.

Although the Butler Act was repealed in 1967 and there's no current move today to ban the teaching of evolution in Tennessee's public schools, introducing students to the subject remains challenging. But it's a challenge the 38-year-old assistant professor has accepted, determined to convince her students that the topic doesn't have to negate science or God.

Thomas Huxley, a contemporary and friend of Charles Darwin, coined the term "agnostic" in 1869 as he was trying to find a way to settle debates about the religious or antireligious nature of science, Barnes notes. 

"Huxley said that science is a process that doesn't have the means to determine whether or not something outside of the natural world is influencing the natural world." 

In other words, science says that evolution happened. How it happened, well, the debate continues and likely will: everything from the creation narrative found in Genesis to the cosmological slow dance of creation that followed the Big Bang.

"But these ideas of deistic, theistic, agnostic and atheistic evolution are equally compatible with what we know from science, because it's not really science's job to tell you whether God exists or whether God had an influence on the natural world," Barnes says.

Science's job, she adds, "is to determine what did happen in the natural world."

Although students in Tennessee's public schools are exposed to evolution in high school biology classes, per the state's science standards, Barnes has found that many of her students don't have a firm understanding of evolution when they arrive at her classroom. That may be because students took biology early in high school and did not retain the material. But many, she says, have concerns about reconciling their faith with science.

Barnes was introduced to evolution in a biology class at a community college. She calls it "one of the most beautiful, amazing ideas that I ever heard of." At the same time, Barnes says she also "learned that about 60 percent of the United States doesn't think that evolution was real."

A year or so later, when she was taking upper-level biology classes at Arizona State University, she was confounded by research professors who "were talking about evolution in a way that kind of put evolution and religion against one another." Although Barnes is not a person of faith, she recognized that fellow students who were churchgoers were wrestling with this teaching approach, sometimes to the point of dropping the class. 

"It seemed to be very conflict-inflating," Barnes says.

She wondered if there wasn't a better way. That prompt led to a major focus of her research: teaching evolution in a manner that reduces conflict. 

In the Bible Belt, many students bring religious values fashioned by teachings that are opposed to evolution, Barnes says. Through her research and teaching, Barnes says she's learned it is possible to nurture scientific inquiry without being dogmatic to the point of negating someone else's faith.

"What we really want them to be able to do is evaluate scientific evidence, you know, apart from their personal biases," she says. "What I've said [to students] is that I don't come in here and teach you science just so you can learn the facts and not be able to do anything with them." 

Her job, she says, is not to make students accept evolution. Every semester, Barnes tells her classes: "It's not my job as an instructor to grade you on what your beliefs are. Or to judge you on what your beliefs are. My job is for you to understand the science."

She's confident her approach has made a difference. 

"I get emails from students, or they come up to me after class, you know, talking about how they have been so relieved to not have to pick between their science and their faith."
...

https://www.nashvillescene.com/news/coverstory/scopes-monkey-trial-100th-anniversary/article_26bbeb9c-a101-41d6-ae51-ca05b23e53cd.html?utm_source=ActiveCampaign&utm_medium=email&utm_content=Scopes%20%22Monkey%20Trial%22%20at%20100&utm_campaign=Daily%20Scene%20071025%20Thursday

Wednesday, July 9, 2025

Changing the tribal mind

From growing up in a highly religious household to becoming a leading evolutionary biologist and broadcaster, Ella Al-Shamahi's story is one of courage, curiosity, and discovery.

https://bsky.app/profile/humanists.uk/post/3lthcxkczts27

Sunday, July 6, 2025

How to Wreck the Nation’s Health, by the Numbers

 Physicians like me know from the data that lives will be lost as a consequence. More than 6,000 health professionals (myself included) have warned the public about their concerns in an open letter. Yet institutions of all kinds seem to be cowering to Mr. Trump, afraid of being punished or prosecuted for questioning his wishes. The administration has defied the courts and gone after law firms and universities, and is unlikely to spare medicine. Just as it has pressured the mediato alter the news, the government is now challenging medical journals to alter what they publish.

Times like these call on us to speak the truth. On matters of life and death, physicians like me have an added duty to warn patients and the public. People may feel that a shakeup in Washington is long overdue. But too many Americans, including our leaders, take their health for granted, assuming that the infrastructure to prevent disease and save their lives will always be there, that America will always lead the world in science and that systems to keep their children safe will always exist. None of this can be counted on, especially now.


https://www.nytimes.com/interactive/2025/06/30/opinion/hhs-cuts-harming-american-health.html?smid=nytcore-ios-share&referringSource=articleShare

Wednesday, July 2, 2025

454 Hints That a Chatbot Wrote Part of a Biomedical Researcher’s Paper

Scientists show that the frequency of a set of words seems to have increased in published study abstracts since ChatGPT was released into the world.

Scientists know it is happening, even if they don't do it themselves. Some of their peers are using chatbots, like ChatGPT, to write all or part of their papers.

In a paper published Wednesday in the journal Science Advances, Dmitry Kobak of the University of Tübingen and his colleagues report that they found a way to track how often researchers are using artificial intelligence chatbots to write the abstracts of their papers. The A.I. tools, they say, tend to use certain words — like "delves," "crucial," "potential," "significant" and "important" — far more often than human authors do.

The group analyzed word use in the abstracts of more than 15 million biomedical abstracts published between 2010 and 2024, enabling them to spot the rising frequency of certain words in abstracts.

The findings tap into a debate in the sciences over when it is and is not appropriate to use A.I. helpers for writing papers...


https://www.nytimes.com/2025/07/02/health/ai-chatgpt-research-papers.html?smid=em-share

Thursday, June 26, 2025

Worst case scenario

RFK Jr. is threatening the foundation of children's health in this country and we all need to be paying attention.

Get loud. Stay loud.

https://www.threads.com/@annieandrewsmd/post/DLWKx3Ax6rw?xmt=AQF04lwq27jsB4yX08K7OIZ6Kf9rk5XDJd9ZRFQb2b02Cg