Friday, April 5, 2019

Quizzes Apr 9, 11

T 9 - Beyond 43-46; Report: Elizabeth

1. The American obsession with abortion distracts US policy from what?

2. Why does assisted reproduction in America get less oversight than many other areas?

3. What ingredients have made the US a destination for hypercontrolling parents?

4. Preselecting _____ traits is no longer the stuff of sci-fi.

5. What's an example of "negative enhancement"?

6. What did Richard Lewontin say about race and genetics?

7. What is the "appeal" of linking race to medical and scientific progress?

8. Racial narratives are always about what?

9. What's the most obvious potential problem raised by the Genographic Project?

10. Docs who use race as a diagnostic "shortcut" are blind to what, and have their attention diverted from what?

DQ
  • Do you agree that the polarized abortion debate in the US distracts policymakers from addressing other serious concerns? How can that be rectified?
  • COMMENT: "The girls can be erased. And the boys remain." 390
  • Is "consumer eugenics" ethically different from eugenics in any other form?
  • Is Lee Silver's Gattaca forecast plausible? 391
  • Is abortion a "red herring"? 
  • Is there any effective way to discourage people from using PGD to "enact their biases"?
  • If we must forever renounce technologies whose use magnifies people's biases, can we continue as a technological species?
  • Dr Steinberg defends PGD as a "service," seeming to imply that its ethical status is not his concern. How should we think about this concept of "service" in medicine, from an ethical perspective?
  • Can discussions of race ever get beyond politicization and "correctness"?
  • Should we challenge "the power of biology as a naturalizing discourse"? 
  • Can or should the social science "consensus" view of race as a social concept be culturally self-fulfilling? Would it be in any sense better for us to affirm this view, whatever the biological science says?
  • COMMENT: "We must abandon any use of race that fails to capturethe true complexity of human genetic variation."408
  • How do you respond to questionnaires that inquire as to your racial identity?

Health news... weekly health news quiz

Carl Zimmer's She Has Her Mother's Laugh: The Powers, Perversions, and Potential of Heredity has interesting things to say about race, and genetics generally.




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Th 11 - Beyond 47-50; Report: Sean. Under construction, add your questions etc.

1. Is BiDil a pharmacogenomic drug?

2. What trendy unfounded argument may segregate medicine, fatten drugmakers' profits, and fail to address the underlying causes of premature African-American mortality?

3. Why did BiDil's developers test it in only one ethnic group?

4. Under what conditions should the FDA grant race-specific approvals?

5. Why should we approach genetic ancestry testing with caution?

6. What do many consumers not realize about DNA tests? Why?

7. Why should doctors be cautious when considering the results of ancestry tests?

8. What makes it difficult for two analysts to come to the same conclusion about fingerprints?

9. Blacks make up what percentage of federal DNA database profiles?

10. How did Lukis Anderson's DNA end up on Raveesh Kumra's body?

DQ

  • Will Pharmacogenomics eventually transform medicine? 
  • What's wrong with "data dredging"? 417
  • How can medical science be appropriately insulated from inappropriate commercial pressures (for instance, to extend the patent life of a particular drug by targeting an arbitrary ethnic group)?
  • If DNA tests examine less than 1% your DNA and shed light on only one ancestor per generation, why are so many of us so enthralled with them? 423
  • Why do so many of us desire proof of native American ancestry, especially given the prevalence of false markers? 425
  • Does "the popular understanding that race is rooted in one's DNA" account for the fascination some have with genetic testing? 
  • Mixed-race people frequently choose a social/racial identity for primarily social/cultural reasons. How does this square with their tendency to seek genetic confirmation of that identity?
  • How can we puncture the "myth of DNA infallibility"? 437



14 comments:

  1. Alt Quiz Questions:

    1. What is one of the themes that cropped up over and over again in Mara Hvistendahl's reporting? (387)
    2. The UK has made perhaps the most ambitious effort at regulation by establishing what? 9389)
    3. What should the anti-abortion movement agree with? (391)
    4. What is PGD? (393)
    5. In October 2007, scientists from deCode genetics published a paper pinpointing what? (395)
    6. How does Evelynn Hammonds characterize the current controversy about the meaning of race? (399)
    7. What was the controversy over the 1994 publication of Richard J. Herrnstein and Charles Murray's book? (405)
    8. Journalists and reputable organization have a duty to reveal what? (407)
    9. What was the race specific medicine that the FDA approved? (413)

    ReplyDelete
    Replies
    1. 1. The extent to which American abortion politics on both sides has stalled action on issues of major global importance.
      2. Human Fertilisation and Embryology Authority (HFEA)
      3. Sex selection, along with many other forms of selection, is wrong.
      4. Preimplantation genetic diagnosis
      5. SNPs that influence skin, hair, and eye color
      6. a "raging debate"
      7. Herrnstein and Murray argued that current woes of the underclass were more a product of biology than justice.
      8. The ethical, legal, financial, and social implications of genetic research that invokes race.
      9. BilDil

      Delete
    2. 1) the extent of Abortion politics which have stalled global importance
      2)HFEA
      3)that sex selection is wrong
      4)preimplantation genetic diagnosis

      Delete
  2. DQ: How do you respond to questionnaires that inquire as to your racial identity?

    "what are you?" is typically the question and I the answer I used to give was Mexican because I realized what they were actually referring too: Ethnic nationalism.
    Now, most of the time I say, well I'm from Texas but my parents are from Mexico. It is a question I have pondered, and have decided to just say...human.

    ReplyDelete
    Replies
    1. I feel like a lot of the time, questions toward your racial identity give way too broad categories to actually learn anything significant. Me saying that I'm caucasian lumps me into a population of billions of other people, and ultimately seems like a pointless question to ask in almost all scenarios.

      Delete
  3. DQ:Is "consumer eugenics" ethically different from eugenics in any other form?

    I don't believe so, because cosmetics should be a choice each individual should take an not inflicted upon someone. In promoting cosmetic eugenics you are implying certain traits are "better" than others, just like racism is a result of our practice of "othering", this is just another symptom of the issue.

    https://www.cnn.com/2018/10/16/us/eugenics-craze-america-pbs/index.html This is an article that discusses a PBS documentary called Eugenics Crusades. It discusses why eugenics was so seductive, worth the watch if you have time. if your cant the article is good!

    Here is the documentary:https://www.pbs.org/wgbh/americanexperience/films/eugenics-crusade/

    ReplyDelete
  4. Extra QQ:
    1)John Hopkins survey found what about the PGD clinics? (p395)
    2)What three findings did the recent US survey find? (p394)
    3)What did chief executive of deCode say about the he opposes and why? (395)
    4)What is the duty of journalists and major news organizations? (p407)
    5)What questions does the debate about the power and authority of genetic information as well as the meaning of race ask? (p408)
    6)Why has the US become the 'wild west" of assisted reproductions? (p389)
    7)True or false,is the US a destination for couples around the world looking for the latest sex selections techniques? (p389)
    8)What did the pioneer of the PGD process say about the response of labs? (p393)

    ReplyDelete
  5. Response to q's
    1. 3% of clinics had provided negative enhancement services
    3. He doesn't condone tailormaking children
    4. To reveal the ethical implications of genetic research
    5. Can genetics tell me us who we are etc
    6. It allows nearly unfettered use of sex selection tech.
    7. True
    8. Legitamate labs won't use Pgd to create designer babies

    ReplyDelete
  6. Alt quiz q's
    1. What do some companies assume about alleles? 424
    2. Current understandings of race and ethnicity reflect more than...?424
    3. What are cold hits? 429
    4. What are genetic informants? 432
    5. What is the significance of the one in 1.1 million chance? 436
    6. What was the name of the NYT article which discussed BiDil? 420
    7. What is AIDSVAX? 421
    8. How is AstraZeneca involved in racializing medicine? 421

    ReplyDelete
    Replies
    1. 1. It is diagnostic about that population.
      2.Genetic Relatedness
      3. They are when investigators are able to match unknown biological materials left at a crime scene with a known database profile.
      4. When the government turns people with existing stored profiles into information regarding relatives without consent or their knowledge of.
      5. That there is a chance that John Puckett was innocent and that the partial match is a coincidence and that this chance was overlooked.
      6. Los Angeles Times
      7. An AIDS vaccine based on retrospective analysis of racial subgroups.
      8. They used race-specific studies to demonstrate the safety and efficacy of Crestor.

      Delete
  7. April 11 Alt. Quiz Questions
    What was BiDil initially used to treat?
    How did doctors treat heart failure before the 1980s?
    Why did the FDA initially refuse to approve BiDil in 1997?
    What small firm in Massachusetts did the FDA give permission to conduct the African American Heart Failure Trial?
    What does AncestryByDNA use to create the appearance of genetically distinct populations?
    How do DNA databases gain much of their authority?
    What chance was the jury told that John Puckett’s DNA was coincidentally misplaced?

    ReplyDelete
  8. 1. Anderson was dangerously close to being put on death row because of what? (437)
    2. ________ is an invaluable tool for law enforcement. (437)
    3. Name a way DNA forensics can lead to injustice. (436)
    4. The ______ report and its recommendation represents an important first step to putting the scientific methods rigor into forensics so that justice can prevail. (432)
    5. What is the significance of the “California Law” passed in 2009? (432)
    6. There is no agreed upon standard for how to calculate what? (430)
    7. When does a partial match occur? (429)
    8. We must weigh the risk and benefits of genetics ancestry testing and the scientific community must do what? (426)
    9. What does ASHG stand for and what did it publish? (426)
    10. It is unlikely that companies deliberately do what? (425)

    ReplyDelete
    Replies
    1. 1)A speck of DNA
      2)DNA forensics
      3)Contamination
      4)NCR
      5)It allows authorities to take and retain DNA samples from individuals that have been arrested for felonies. They don't have to be charged or convicted.
      6)On how to present or calculate DNA evidence in court.
      7)When the investigators identify a suspect using fewer than thirteen loci.
      8)Make clear the limitations and potential dangers of genetic ancestry testing, beginning by breaking the silence.
      9)American Society of Human Genetics and they published a series of recommendations regarding the direct to consumer genetic tests that make health related claims.
      10)choose to mislead consumers or misrepresent science.

      Delete
  9. Discussion Question:

    If DNA forensics and fingerprinting is not as conclusive in criminal cases as what is popularly advertised, why is it treated as such?

    ReplyDelete