Up@dawn 2.0

Friday, August 22, 2025

"William James, MD: Philosopher, Psychologist, Physician"

"James was awarded his MD from Harvard Medical School in March 1869, after more than five years of interrupted study. This certificate lists his examiners, who included Oliver Wendel Holmes Sr., and the subject of his thesis, namely, the effects of cold on the body. (Diplomas, degrees, notifications of appointments, etc., William James papers [MS Am 1092.9–1092.12, MS Am 1092.9 (4571), Box: 40], Houghton Library, Harvard University.)

There is one element of James’s life and work that unites these disparate identities, however. In 1869, several years before he secured his first lectureship, he graduated from Harvard Medical School and earned his MD. Hampered by his own ill health, James abandoned his plans to practice as a doctor, but these studies were only the beginning of a profound and lifelong occupation with questions about the essential nature of health, healing, and invalidism and their implications for society. His writings, across their disciplinary breadth, return time after time to issues of a medical provenance. In this book I make the case that James’s medical interests, concerns, and values are the threads that bind many of his seemingly unconnected pursuits together. They are the warp and weft of many of his best-known publications and major lines of thought."
...
"William James, MD: Philosopher, Psychologist, Physician" by Emma K. Sutton: https://a.co/4PTkAZq

Wednesday, August 20, 2025

Can’t argue with that

NYTimes: What Happens to Your Brain When You Retire?

"There is great evidence that finding meaning in life gives one a great personal satisfaction."

https://www.nytimes.com/2025/03/26/well/mind/retirement-brain-mental-health-tips.html?smid=nytcore-ios-share&referringSource=articleShare

Monday, August 18, 2025

NYTimes.com: What My Daughter Told ChatGPT Before She Took Her Life

The medical profession has clear rules and responsibilities. What about the chatbots?

...Increasingly, people with mental health conditions are using large language models for support, even though researchers find A.I. chatbots can encourage delusional thinking or give shockingly bad advice. Surely some benefit. Harry said many of the right things. He recommended Sophie seek professional support and possibly medication; he suggested she make a list of emergency contacts; he advised her to limit access to items she might use to harm herself.

Harry didn't kill Sophie, but A.I. catered to Sophie's impulse to hide the worst, to pretend she was doing better than she was, to shield everyone from her full agony. (A spokeswoman for OpenAI, the company that built ChatGPT, said it was developing automated tools to more effectively detect and respond to a user experiencing mental or emotional distress. "We care deeply about the safety and well-being of people who use our technology," she said.)

In December, two months before her death, Sophie broke her pact with Harry and told us she was suicidal, describing a riptide of dark feelings. Her first priority was reassuring her shocked family: "Mom and Dad, you don't have to worry."

Sophie represented her crisis as transitory; she said she was committed to living. ChatGPT helped her build a black box that made it harder for those around her to appreciate the severity of her distress. Because she had no history of mental illness, the presentable Sophie was plausible to her family, doctors and therapists...

https://www.nytimes.com/2025/08/18/opinion/chat-gpt-mental-health-suicide.html?smid=em-share

Thursday, August 14, 2025

Margaret Boden, Philosopher of Artificial Intelligence, Dies at 88

A cognitive scientist, she used the language of computers to explore the nature of human thought and creativity, offering prescient insights about A.I.

...She was among the skeptics.

“The notion of there ever being a time where we could have a natural language-using program which was able really to converse in a rich and subtle way with an intelligent and educated human being about anything under the sun — from, you know, football to fossils — seems to me to be a fantasy,” she said on “The Life Scientific.”


Today, such abilities actually exist with large language models like ChatGPT. Professor Boden entered a care home before these tools emerged and wasn’t able to use them.


I put the question to ChatGPT: Would Professor Boden have been surprised by its existence?


“Margaret Boden probably wouldn’t have been shocked that something like ChatGPT exists — but she would likely have been both fascinated and deeply critical,” ChatGPT responded. “She stressed that computers don’t ‘think’ or ‘understand’ in the way humans do — they manipulate symbols without consciousness or intentionality.”


...

https://www.nytimes.com/2025/08/14/science/margaret-boden-dead.html?smid=em-share

Tuesday, August 5, 2025

How to Live Forever and Get Rich Doing It

As researchers work to make death optional, investors see a chance for huge returns. But has the human body already reached its limits?

https://www.newyorker.com/magazine/2025/08/11/how-to-live-forever-and-get-rich-doing-it

Sunday, July 27, 2025

Joyspan

 Joyspan is a term coined by Kerry Burnight… In her upcoming book, "Joyspan: The Art and Science of Thriving in Life's Second Half," she says that a lengthy life span does not equal a life well lived: You have to like your life, too...

https://www.nytimes.com/2025/07/18/well/is-joyspan-the-key-to-aging-well.html?smid=nytcore-ios-share&referringSource=articleShare

Tuesday, July 15, 2025

The 1st flu vaccine

Today is the birthday of microbiologist Thomas Francis Jr., born in Gas City, Indiana (1900). T.F., as he was known to his friends, grew up in western Pennsylvania and studied medicine at Yale. He graduated in 1925. His early research projects involved bacterial pneumonia, but he was particularly interested in the study of viruses. He was the first American to isolate the human influenza virus.

He joined the University of Michigan in its newly formed School of Public Health in 1941. It was here that he developed the first flu vaccine, which used the dead influenza virus to provoke an immune response in the human body. Francis had discovered in 1940 that there was more than one kind of flu virus. That's why epidemiologists release a different flu vaccine every year, based on their predictions of which strains will be dominant. It's estimated that Francis's flu vaccine has directly saved more than a million lives.

While he was teaching at the University of Michigan, Francis established a virology lab to study viruses. One of his first students in the lab was Jonas Salk. Francis taught his student how to develop vaccines, and Salk eventually went on to develop a vaccine against polio. Francis designed the massive nationwide field trial that proved the effectiveness and safety of Salk's vaccine.

Francis also founded the University of Michigan's Department of Epidemiology, to study how diseases are spread through populations and develop ways of controlling outbreaks. Francis said: "Epidemiology must constantly seek imaginative and ingenious teachers and scholars to create a new genre of medical ecologists who, with both the fine sensitivity of the scientific artist and the broad perception of the community sculptor, can interpret the interplay of forces which result in disease."

https://www.garrisonkeillor.com/radio/the-writers-almanac-for-tuesday-july-15-2025/

Thursday, July 10, 2025

Scopes at 100: America Is Still Animated by the Scopes ‘Monkey Trial’ | Cover Story | nashvillescene.com

...The challenge with teaching evolution in 2025 is the same each semester, says Elizabeth Barnes, who is now approaching her fifth year on the biology faculty at Middle Tennessee State University.

"I would say one of the biggest things that we face when we go to teach evolution is this perception that in order to accept evolution, to actually believe that evolution is a real thing, that you have to be an atheist or reject religious belief," Barnes says.

A national survey of biology students conducted by Barnes and other researchers in 2022 showed that 50 percent of the respondents believed acceptance of evolution was a rejection of God.

"That's just a misunderstanding of the nature of science," Barnes says.

Although the Butler Act was repealed in 1967 and there's no current move today to ban the teaching of evolution in Tennessee's public schools, introducing students to the subject remains challenging. But it's a challenge the 38-year-old assistant professor has accepted, determined to convince her students that the topic doesn't have to negate science or God.

Thomas Huxley, a contemporary and friend of Charles Darwin, coined the term "agnostic" in 1869 as he was trying to find a way to settle debates about the religious or antireligious nature of science, Barnes notes. 

"Huxley said that science is a process that doesn't have the means to determine whether or not something outside of the natural world is influencing the natural world." 

In other words, science says that evolution happened. How it happened, well, the debate continues and likely will: everything from the creation narrative found in Genesis to the cosmological slow dance of creation that followed the Big Bang.

"But these ideas of deistic, theistic, agnostic and atheistic evolution are equally compatible with what we know from science, because it's not really science's job to tell you whether God exists or whether God had an influence on the natural world," Barnes says.

Science's job, she adds, "is to determine what did happen in the natural world."

Although students in Tennessee's public schools are exposed to evolution in high school biology classes, per the state's science standards, Barnes has found that many of her students don't have a firm understanding of evolution when they arrive at her classroom. That may be because students took biology early in high school and did not retain the material. But many, she says, have concerns about reconciling their faith with science.

Barnes was introduced to evolution in a biology class at a community college. She calls it "one of the most beautiful, amazing ideas that I ever heard of." At the same time, Barnes says she also "learned that about 60 percent of the United States doesn't think that evolution was real."

A year or so later, when she was taking upper-level biology classes at Arizona State University, she was confounded by research professors who "were talking about evolution in a way that kind of put evolution and religion against one another." Although Barnes is not a person of faith, she recognized that fellow students who were churchgoers were wrestling with this teaching approach, sometimes to the point of dropping the class. 

"It seemed to be very conflict-inflating," Barnes says.

She wondered if there wasn't a better way. That prompt led to a major focus of her research: teaching evolution in a manner that reduces conflict. 

In the Bible Belt, many students bring religious values fashioned by teachings that are opposed to evolution, Barnes says. Through her research and teaching, Barnes says she's learned it is possible to nurture scientific inquiry without being dogmatic to the point of negating someone else's faith.

"What we really want them to be able to do is evaluate scientific evidence, you know, apart from their personal biases," she says. "What I've said [to students] is that I don't come in here and teach you science just so you can learn the facts and not be able to do anything with them." 

Her job, she says, is not to make students accept evolution. Every semester, Barnes tells her classes: "It's not my job as an instructor to grade you on what your beliefs are. Or to judge you on what your beliefs are. My job is for you to understand the science."

She's confident her approach has made a difference. 

"I get emails from students, or they come up to me after class, you know, talking about how they have been so relieved to not have to pick between their science and their faith."
...

https://www.nashvillescene.com/news/coverstory/scopes-monkey-trial-100th-anniversary/article_26bbeb9c-a101-41d6-ae51-ca05b23e53cd.html?utm_source=ActiveCampaign&utm_medium=email&utm_content=Scopes%20%22Monkey%20Trial%22%20at%20100&utm_campaign=Daily%20Scene%20071025%20Thursday

Wednesday, July 9, 2025

Changing the tribal mind

From growing up in a highly religious household to becoming a leading evolutionary biologist and broadcaster, Ella Al-Shamahi's story is one of courage, curiosity, and discovery.

https://bsky.app/profile/humanists.uk/post/3lthcxkczts27

Sunday, July 6, 2025

How to Wreck the Nation’s Health, by the Numbers

 Physicians like me know from the data that lives will be lost as a consequence. More than 6,000 health professionals (myself included) have warned the public about their concerns in an open letter. Yet institutions of all kinds seem to be cowering to Mr. Trump, afraid of being punished or prosecuted for questioning his wishes. The administration has defied the courts and gone after law firms and universities, and is unlikely to spare medicine. Just as it has pressured the mediato alter the news, the government is now challenging medical journals to alter what they publish.

Times like these call on us to speak the truth. On matters of life and death, physicians like me have an added duty to warn patients and the public. People may feel that a shakeup in Washington is long overdue. But too many Americans, including our leaders, take their health for granted, assuming that the infrastructure to prevent disease and save their lives will always be there, that America will always lead the world in science and that systems to keep their children safe will always exist. None of this can be counted on, especially now.


https://www.nytimes.com/interactive/2025/06/30/opinion/hhs-cuts-harming-american-health.html?smid=nytcore-ios-share&referringSource=articleShare

Wednesday, July 2, 2025

454 Hints That a Chatbot Wrote Part of a Biomedical Researcher’s Paper

Scientists show that the frequency of a set of words seems to have increased in published study abstracts since ChatGPT was released into the world.

Scientists know it is happening, even if they don't do it themselves. Some of their peers are using chatbots, like ChatGPT, to write all or part of their papers.

In a paper published Wednesday in the journal Science Advances, Dmitry Kobak of the University of Tübingen and his colleagues report that they found a way to track how often researchers are using artificial intelligence chatbots to write the abstracts of their papers. The A.I. tools, they say, tend to use certain words — like "delves," "crucial," "potential," "significant" and "important" — far more often than human authors do.

The group analyzed word use in the abstracts of more than 15 million biomedical abstracts published between 2010 and 2024, enabling them to spot the rising frequency of certain words in abstracts.

The findings tap into a debate in the sciences over when it is and is not appropriate to use A.I. helpers for writing papers...


https://www.nytimes.com/2025/07/02/health/ai-chatgpt-research-papers.html?smid=em-share

Thursday, June 26, 2025

Worst case scenario

RFK Jr. is threatening the foundation of children's health in this country and we all need to be paying attention.

Get loud. Stay loud.

https://www.threads.com/@annieandrewsmd/post/DLWKx3Ax6rw?xmt=AQF04lwq27jsB4yX08K7OIZ6Kf9rk5XDJd9ZRFQb2b02Cg

Sunday, June 1, 2025

The Techno-Futuristic Philosophy Behind Elon Musk’s Mania

"…The balance of evidence is such that it would appear unreasonable not to assign a substantial probability to the hypothesis that an existential disaster will do us in," Bostrom wrote, adding later in the paper, "With technology, we have some chance, although the greatest risks now turn out to be those generated by technology itself."

Whether or not Musk read the paper, he has echoed Bostrom and other proponents of longtermism, including the philosopher William MacAskill. MacAskill became something of a celebrity intellectual among technologists and financiers, to whom he preached an "earning-to-give" approach to philanthropy. Sam Bankman-Fried, the now disgraced crypto magnate, was one of his biggest acolytes. Musk touted MacAskill's 2022 book, "What We Owe the Future," saying on X — the social media network that he owns — that the explication of longtermist thinking is "a close match to my philosophy."

https://www.nytimes.com/2025/05/29/business/elon-musk-longtermism-effective-altruism-doge.html?smid=nytcore-ios-share&referringSource=articleShare

Monday, May 26, 2025

Brain (& heart) drain

Dr. Timothy Johnson, longtime network TV medical reporter and founding editor of the Harvard Medical School Health Letter, says that by cutting more than $1.8 billion in grants from the National Institutes of Health, the Trump administration risks destroying U.S. medical research infrastructure and prompting a "brain drain" of scientists to other countries. https://cbsn.ws/4jgJp6I

Tuesday, May 20, 2025

The President Will Destroy You Now

"…This is going to completely kneecap biomedical research in this country," Jennifer Zeitzer, the deputy executive director at the Federation of American Societies for Experimental Biology, told Science magazine. Georges Benjamin, the executive director of the American Public Health Association, warned that cuts will "totally destroy the nation's public health infrastructure."
https://www.nytimes.com/2025/05/20/opinion/trump-musk-doge-government.html?smid=nytcore-ios-share&referringSource=articleShare

Monday, May 19, 2025

The best in us

Born on this day in 1872, Bertrand Russell lived nearly a century, through two world wars, and won the Nobel Prize for his timeless writing that champions the best in us: our kindness, our critical thinking, our freedom of being. His immortal wisdom on how to grow old and what makes a fulfilling life:

https://www.themarginalian.org/2018/07/03/how-to-grow-old-bertrand-russell/

Sunday, May 18, 2025

Go to Mars, Never Die and Other Big Tech Pipe Dreams

 One prominent paper concluded that $100 spent on A.I. safety saves one trillion future lives — making it "far more" valuable "than the near-future benefits" of distributing anti-malarial bed nets. "For a strong longtermist," Becker writes, "investing in a Silicon Valley A.I. safety company is a more worthwhile humanitarian endeavor than saving lives in the tropics." 

Tech billionaires' pet projects can sound deliriously futuristic, but lurking underneath them all is an obsession that is very old. It's the primal fear of death, encased in a shiny new rocket ship. Becker quotes other writers who have noticed how Silicon Valley, with its omnivorous appetite, has turned existential angst into yet another input. "Space has become the ultimate imperial ambition," the scholar Kate Crawford writes in "Atlas of A.I.," "symbolizing an escape from the limits of Earth, bodies and regulation." In "God, Human, Animal, Machine" (2021), Meghan O'Gieblyn describes how technology took over the domain of religion and philosophy: "All the eternal questions have become engineering problems."

The "ideology of technological salvation" that Becker identifies can therefore be understood, too, as a desperate attempt to deal with despair. Amid his sharp criticisms of the tech figures he writes about is a resolute call for compassion. He encourages us not to get hung up on galaxies far, far away but to pay more attention to our own fragile planet and the frail humans around us.

"We are here now, in a world filled with more than we could ever reasonably ask for," Becker writes. "We can take joy in that, and find satisfaction and meaning in making this world just a little bit better for everyone and everything on it, regardless of the ultimate fate of the cosmos."

https://www.nytimes.com/2025/04/23/books/review/more-everything-forever-adam-becker.html?smid=nytcore-ios-share&referringSource=articleShare