Friday, March 25, 2022

Questions MAR 29

Beyond 23-27, Lifelines 8-9 

Time to select final report topics, presentations to follow same order as midterm reports. Try to relate your topic to the texts we're reading now, even if you're expanding on your midterm presentation theme. 

Remember, the accompanying final blog post is due April 29 but you can post earlier drafts if you want potentially-helpful constructive feedback. I'll send author invitations out soon, to those who need them.

1. In this touted Age of Genomics, what frequently follows the hopeful hype about gene therapy?

2. Steve Jones says we know what of genetics?

3. What was Francis Collins' prediction in 2000? In 2014?

4. What's the best way to engineer a tall person, and what does that tell us about the effects of "Many Assorted Genes..."?

5. "Anonymous" tissue samples can be what?

6. What is Jessica Cussins' practical objection to the results of DTC genetic tests?

7. What more than doubled in illustration of the "Angelina Jolie effect"?

8. There aren't enough what to support population-wide screening for the BRCA genes?

9. The UC-Berkeley DNA project was intended to introduce students to what?

10. How should leading geneticists have responded to loose talk in the early '90s (and still) about "the gay gene," "the violence gene," etc.?


DQ
  • Who's responsible for over-hyping the promise of gene therapy?
  • Why is the history of genomics so full of unfulfilled promise?
  • If short people are discriminated against, is the solution to engineer tall people? Or to oppose discrimination more aggressively?
  • Do you agree that we should divert billions from genomic research to behavioral modification? 249
  • Why do patients who support genomic research nonetheless "want to be informed..."? 251
  • Is there any reason in principle why 23andMe's algorithm could not be corrected to detect and distinguish gene mutations that are and are not life-threatening? 253
  • Is there anything ethically wrong with women electing for prophylactic mastectomies?
  • Do the risks of universal screening for the BRCA genes outweigh the benefits? 
  • If there were enough genetic counselors to support population-wide screening, would you support it?
  • Should patients be informed of mutations that are not found to correlate with increased cancer risk? 257
  • Is it in fact "common knowledge" that there isn't a gene for homosexuality, etc.?

Lifelines
1. What was Leana's simple question? How did nurses and social workers respond?

2. What's Leana's motto? What was an example (besides waiting for the "high-tech dashboard") of its violation?

3. What was Leana's "singular dream"?

4. Which hospitals make the most progress?

5. What did the new mayor say about patients seeking treatment for addiction?

6. What luxury can those of the front lines of public health not afford?

7. What three things was Leana unwilling to do?

8. What does Leana see as the cause(s) of drug addiction?

9. What did health clinics (like libraries, schools, and senior centers) represent to a community under siege?

10. What's a PIO?

11. What is public health's moral imperative?

12. Leana's philosphy is what?
DQ
  • Do you agree with the policy of making naloxone readily available to drug abusers, educating them about the dangers of drug abuse, asking that they not use drugs alone, etc.? 128
  • Aren't "work-arounds" like getting people in the field to share emergency information promptly just common sense? Why must common-sense solutions so often be improvised in an administrative system, rather than integrated with its structure?
  • Is it a good idea to collaborate and engage with the private sector, to promote public health? 129
  • Is it a mistake to launch programs like "Bad Batch" without evidence that they work? Is failure a "necessary part of progress" in the deployment of such programs? 130
  • Would you have confronted the new mayor or tried to work with and educate her as Leana did?
  • What do you think accounts for the change of attitude regarding drug treatment, between 2014 and 2018?141
  • Why is public health "often overlooked" in a crisis? 144





Health news... Weekly health quiz... WHQ 3/8... WHQ 3/3...  Treating Alzheimer's... Her son died. And then anti-vaxers attacked her

9 comments:

  1. (DQ) Do you agree that we should divert billions from genomic research to behavioral modification? 249

    I honestly hadn't given much thought to this before reading about it. Honestly, maybe it's not such a bad idea. Most behavioral disorders affect average people every day, disorders that are not genome-derived. If researchers had the funds available, we could begin to imagine a world without depression, anxiety, bipolar disorder, even sociopathic disorders. We could treat violent people and alter their behavior completely, which could lead us to diminish the prison population. There are certain drawbacks, such as the regulation of this type of treatment; as always, there are probably bad people that would use this technology to wipe out individuality and unique personalities in the name of conformity. Genomic research is important as well, but I think a lack of funding in behavioral research causes a lot of unnecessary problems.

    ReplyDelete
  2. 12. Leana's philosophy is what?
    Her philosophy is that "pragmatism wins out over idealism every time." She makes a point to discuss that we can't wait around for a perfect policy or time/place. It is interesting because we often admire those who may take "principled" stances against something. But I feel like Leana is kind of arguing against that. It's about working with what you have and being willing to compromise.

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  3. DQ: Is there anything ethically wrong with women electing for prophylactic mastectomies?

    Some people elect to do medical procedures like cosmetic surgeries that have nothing to do with their health. So, I don't see anything ethically wrong with a woman choosing to have a mastectomy to prevent an extremely prevalent disease. I think being informed is where the ethics may come in: making sure people are fully aware of the risk and consequences of the surgery and also the risk to develop breast cancer. Sometimes you may have a mutation but that doesn't always mean you will get cancer for certain. The public should definitely consult genetic counselors or other professionals to help interpret any type of genetic testing before making major life choices.

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  4. 9. The UC-Berkeley DNA project was intended to introduce students to what?

    "The UC Berkeley DNA project is being promoted with the explicit goal of introducing students to a future of personalized medicine, via the analysis of an individual's genes."

    ReplyDelete
  5. 8. There aren't enough what to support population-wide screening for the BRCA genes?

    "Unfortunately, there aren't even enough trained genetic counselors to attend to the number of people who are getting BRCA testing now."

    ReplyDelete
  6. 7. What more than doubled in illustration of the "Angelina Jolie effect"?

    The number of DNA tests for breast cancer mutations.

    ReplyDelete
  7. What is public health's moral imperative?
    Public Health’s moral imperative is to see the people that society prefers not to see and the media chooses not to portray.

    ReplyDelete
  8. Leana's philosophy is what?
    Pragmatism wins out over idealism everytime.

    ReplyDelete
  9. What was Leana's "singular dream"?
    Leana’s singular dream was what if there was an ER dedicated just for addiction and mental health treatment.

    ReplyDelete